Small peptide recognition sequence for intracellular sorting
نویسندگان
چکیده
منابع مشابه
Intracellular mechanisms of molecular recognition and sorting for transport of large extracellular matrix molecules.
Extracellular matrix (ECM) proteins are biosynthesized in the rough endoplasmic reticulum (rER) and transported via the Golgi apparatus to the extracellular space. The coat protein complex II (COPII) transport vesicles are approximately 60-90 nm in diameter. However, several ECM molecules are much larger, up to several hundreds of nanometers. Therefore, special COPII vesicles are required to co...
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ژورنال
عنوان ژورنال: Current Opinion in Biotechnology
سال: 2010
ISSN: 0958-1669
DOI: 10.1016/j.copbio.2010.08.007